The Cost of Turnover in Clinical Operations: What Leaders Can Actually Do About It

Turnover in clinical operations is often discussed as an unfortunate reality of a demanding industry. Long hours, aggressive timelines, and increasing complexity are cited as unavoidable contributors. But after more than two decades leading clinical teams across sponsor and contract research organization environments, the author of this column has come to see turnover differently.

A Practical Guide to Patient-Centric Trials Using Net Treatment Benefit

For many early-career clinical researchers, trial design can feel rigid. A primary endpoint is selected, the study is powered around it, and success is determined by that single measure. But patients do not experience treatment effects through one outcome. They experience a combination of efficacy, side effects, symptoms, and quality of life. Reducing this to a single outcome can risk missing the bigger picture.

A Visit with Mo Ali, the 2026 ACRP Board of Trustees Chair

As experienced pharmaceutical industry executive Mo Ali settled into his volunteer duties as Chair of the ACRP Board of Trustees for 2026, a year in which the Association celebrates its 50th anniversary of service to its members and stakeholders, he took time to answer some questions about his experience in the clinical research enterprise, some of the challenges and opportunities facing it, and how ACRP can further its mission in a time of rapidly evolving technologies and processes.