CDISC-Gloss – A trial that compares health interventions in a diverse population representing clinical practice. These trials inform a clinical or policy decision by providing evidence for adoption of the intervention into real-world clinical practice. NOTE: These trials may or may not be randomized and can be large simple studies. [After GetReal – Project No. 115546l, WP1: Deliverable D1.3, Glossary of Definitions of Common Terms; Ford I, Norrie
J. Pragmatic trials. N Engl J Med. 2016; 375:454-63.] See also Real-World Data (RWD), Real- World Evidence (RWE), confirmatory trial.