Insights

Unlike traditional clinical outcome assessments, which rely on intermittent and sometimes subjective clinic-based measurements, digital biomarkers enable a richer, more dynamic understanding of disease progression and treatment response. This article provides examples of how digital biomarkers are revolutionizing clinical trials, focusing on the authors' shared experiences managing trials within the fields of neurology and oncology.

Stepping into leadership can be daunting. Whether it is becoming a line manager, or leading a study for the first time, as careers progress, priorities shift and more emphasis is placed on interpersonal and organizational skills. This can lead to self-doubt for first-time managers. A quarter of managers say they did not feel ready to lead others when they were first appointed.

The clinical trial industry has a problem--one that is exacerbated by flawed protocol designs, unrealistic inclusion/exclusion criteria, and other factors. Put simply, the industry must finally design trials around real-world patients and stop extrapolating narrow clinical trial data to wider patient populations.

Ethical compliance is the backbone of trustworthy clinical research. However, violations continue to occur, jeopardizing participant safety and data integrity. This article highlights key examples of ethical violations in clinical trials, outlines how clinical research professionals can detect them, and provides guidance on reporting procedures.

With recent integrations of artificial intelligence (AI) into many processes and workflows we touch on a day-to-day basis, it is imperative that ACRP and The Academy of Clinical Research Professionals (The Academy) investigate the use and utility of incorporating AI into the exam development process.